Department of Biological Sciences

Catherine Miller-Hunt, Assistant Professor

Virology, innate immunology

catContact Information:

(309) 298-1294
Office: Waggoner Hall 283
Lab: Waggoner Hall 279 

The Miller-Hunt Lab Official Website:

Ph.D. - University of Iowa, 2010
M.S. - University of Iowa, 2006
B.A. - Western Illinois University, 2002

Courses Taught:

  • MICR 200 Introduction to Microbiology
  • MICR 463G Pathogenic Bacteriology
  • MICR 405 Virology
  • MICR 434 Immunology


Research Interests:

My laboratory is interested in studying how human viruses get into cells of the innate immune system. We are currently focusing on molecules that are up-regulated during innate immune cell maturation and whether these molecules are involved in viral binding and entry into these cells. We are also interested in studying how human viruses manipulate cells of the innate immune system to promote efficient viral replication and spread.  


  • 2015.  Interferon-γ inhibition of Ebola virus infection. Bethany A. Rhein, Linda S Powers, Manu Anantpadma, Yasuteru Sakurai, Thomas Bair, Catherine Miller-Hunt, Robert A. Davey, Martha M. Monick, and Wendy Maury. PLoS Path. Submitted.
  • 2015.  Modeling reproduction under phenotypic plasticity, with whitetail deer as a case study. Dinesh B. Ekanayake, Amy J. Ekanayake, Jason Hunt and Catherine L. Miller-Hunt. Theoretical Population Biology. Submitted.
  • 2015. Presence of the Black-Legged Tick (Ixodes scapularis) in Hancock County, Illinois.Sarah Warren, Jeffery P. Woodyatt, Seán Jenkins, R. Philip Scheibel, Charles Lydeard, and Catherine Miller-Hunt. Transactions of the Illinois State Academy of Science. Submitted.
  • 2015. Efficacy of VSV pseudotyped with Ebola virus GP and N-linked glycan site mutants as non-infectious vaccines against lethal homologous challenge in mice. Nicholas J. Lennemann, Andrew S. Herbert, Rachel Brouillette, Bethany Rhein, Russell Al. Bakken, Julia Biggins, Katherine J. Perschbacher, Ashley Cooney, Catherine M. Hunt, Gene G. Olinger, John M. Dye and Wendy Maury. J Virol. Submitted.
  • 2015.  The nectin-4/afadin protein complex and destabilized cytoskeleton contribute to rapid cell-to-cell spread of measles virus in primary human airway epithelial cells. Brajesh Singh, Anna Locke, Andrew Hornick, Sateesh Krishnamurthy, Catherine L. Miller-Hunt, Mathiew Mateo, Robert Cattaneo, and Patrick L. Sinn. J Virol. In press.
  • 2014.  The 2014 West African Ebola Virus Disease Situation: A Filoviral Outbreak of Pandemic Proportions. Catherine L. Miller-Hunt. Peoria Med J. In press.
  • 2013. AMP-activated protein kinase is required for the macropinocytic internalization of ebolavirus. Andrew Kondratowicz, Catherine Hunt, Robert Davey, Sara Cherry, and Wendy Maury. J. Virol. 87(2):746-55.
  • 2012. Filovirus entry: a novelty in the viral fusion world. Catherine L. Hunt, Nicholas Lennemann and Wendy Maury. Viruses4:258-275.
  • 2011. T-cell immunoglobulin and mucin domain protein 1 (TIM-1) is a receptor for Zaire ebolavirus and Lake Victoria marburgvirus. Kondratowicz, A., Sinn, P.L., Davey, R.A., Hunt, C.L., Lennemann, N.J., Moller-Tank, S.,Meyerholz, D., Rennert, P.D., Mullins, R., Brindley, M., Sandersfeld, L.M., Quinn, K., Weller, M., McCray, Jr., P.B., Chiorini, J.A., and Maury, W.Proc. Natl. Acad. Sci. USA. 108(20):8426-31.
  • 2011. Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoprotein. Hunt, C.L., Brindley, M.A., Kondratowicz, A., Bowman, J., Kolokoltsov, A.A., Davey, R.A., Quinn, K., Weller, M., Sinn, P., McCray, P.A., Chiorini, J.A., and Maury, W. Virology. 415(2):83-94.
  • 2010. The Tyro3 receptor kinase Axl enhances macropinocytosis of Zaire ebolavirus. Catherine L. Hunt, Andrey A. Kolokoltsov, Robert A. Davey and Wendy Maury. J. Virol. 85(1):334-47.
  • 2009. Rho GTPases modulate entry of Ebola virus and vesicular stomatitis virus pseudotyped vectors. Kathrina Quinn, Melinda A. Brindley, Melodie L. Weller, Nikola Kaludov, Andrew Kondratowicz, Catherine L. Hunt, Patrick L. Sinn, Paul B. McCray, Jr., Colleen S. Stein, Beverly L. Davidson, Ramon Flick, Robert Mandell, William Staplin, Wendy Maury and John A Chiorini. J. Virol. 83(19):10176-86.
  • 2006. Effect of D-alanylation of (lipo)teichoic acids of Staphylococcus aureus on host secretory phospolipase a2 action before and after phagocytosis by human neutrophils. Catherine Hunt, William Nauseef and Jerrold Weiss. J. Immunol. 176(8):4987-94.